Individuals with ESRD: Minimal encounter; there are actually postmarketing studies of acute renal failure and worsening of Long-term renal failure, which may often need hemodialysis; use caution in individuals who expertise dehydration
Race and ethnicity experienced no effect on the pharmacokinetics of liraglutide according to the final results of inhabitants pharmacokinetic analyses that integrated overweight and obese people of Caucasian, Black, Asian and Hispanic/Non-Hispanic teams.
Keep an eye on Carefully (one)desogestrel decreases consequences of liraglutide by pharmacodynamic antagonism. Use Caution/Monitor. Oral contraceptives could reduce hypoglycemic consequences of antidiabetics by impairing glucose tolerance. Observe for glycemic Manage in diabetic sufferers.
Saxenda® should be applied with a decreased calorie diet regime and greater physical activity. Saxenda® and Victoza® hold the very same Lively component, liraglutide, and shouldn't be utilised together or with other GLP-1 receptor agonist medicines
captopril raises consequences of liraglutide by not known mechanism. Use Warning/Keep track of. ACE inhibitors may well maximize hypoglycemic result. Monitor glycemic Management Particularly throughout the first thirty day period of therapy by having an ACE inhibitor. .
Saxenda doesn’t perform right away. Nevertheless, convey to your Health care service provider for those who haven’t lost a minimum of 4% of The body bodyweight just after four months website of Saxenda treatment method.
For folks attempting—and having difficulties—to obtain a wholesome weight, the old guidance to “just try to eat considerably less and work out much more” isn’t quite beneficial (and will motivate a reasonably harmful marriage with The body).
Use Warning/Keep an eye on. Antidiabetic agents are often employed together; dosage adjustments may very well be required when initiating or discontinuing antidiabetic agents.
Thiazide diuretics can lower insulin sensitivity therefore resulting in glucose intolerance and hyperglycemia. Keep track of glycemic Handle especially when initiating, discontinuing, or growing thiazide diuretic dose.
eight mg did not produce QTc prolongation. The utmost liraglutide plasma concentration (Cmax) in overweight and obese topics taken care of with liraglutide 3 mg is comparable on the Cmax noticed during the liraglutide QTc review in balanced volunteers.
liraglutide, insulin frequent human. Both boosts consequences of the other by pharmacodynamic synergism. Use Warning/Observe. Antidiabetic agents are sometimes utilized together; dosage changes can be essential when initiating or discontinuing antidiabetic agents.
It isn't acknowledged if SAXENDA is Risk-free and productive when taken with other prescription around-the-counter medicines or herbal weight loss products.
have critical problems with your stomach, for example slowed emptying of the tummy (gastroparesis) or problems with digesting food items
etonogestrel decreases consequences of liraglutide by pharmacodynamic antagonism. Use Caution/Watch. Etonogestrel may possibly lessen hypoglycemic outcomes of antidiabetics by impairing glucose tolerance. Monitor for glycemic Management in diabetic clients.